The Coastal Plain League announced that 39 players, both former and players signed for the 2000 season, were drafted in the 2000 Major League Baseball First-Year Player Draft. Former Wilmington Shark, Tagg Bozied lead this year’s group of alums. Bozied was selected by the Minnesota Twins in the second round, 42nd overall. The Wilmington Sharks had the largest number of former players drafted with nine. This year’s draft far exceeded last year’s total of 24 and 1998’s total of 12.
The complete list of CPL players drafted follows:
| Round | Overall | Player | College/University | MLB Team Drafted By | CPL Team(s) |
|---|---|---|---|---|---|
| 2 | 42 | Tagg Bozied | San Francisco | Minnesota | ’98 Wilmington |
| 3 | 76 | Nick Jackson | Richmond | Chicago (NL) | ’98 Rocky Mount |
| 3 | 91 | Brion Treadway | North Carolina | San Francisco | ’98 Rocky Mount |
| 4 | 103 | Todd Wellemeyer | Bellamine College | Chicago (NL) | ’99 Thomasville |
| 4 | 111 | Eric Henderson | North Carolina | Milwaukee | ’98 Rocky Mount |
| 5 | 155 | Quenten Patterson | Oklahoma State | New York (NL) | ’98 Rocky Mount |
| 6 | 189 | Scott Barber | South Carolina | Arizona | ’98 Wilson |
| 8 | 236 | Rett Johnson | Coastal Carolina | Seattle | ’98 Rocky Mount/ ’99 Durham |
| 8 | 237 | Jason Hickman | Ball State | Los Angeles | ’99 Wilson |
| 8 | 242 | Brian Adams | Liberty | Boston | ’98 Rocky Mount |
| 12 | 350 | Scott Schneider | Norfolk State | Anaheim | ’99 Wilson |
| 12 | 365 | Todd Faulkner | Auburn | New York (NL) | ’98 Wilmington |
| 13 | 382 | Derek Wigginton | Alabama | Chicago (AL) | ’98 Wilmington |
| 13 | 396 | Jeff Hasse | Cleveland State | Cleveland | ’98 Edenton |
| 14 | 401 | Robert Jones | William & Mary | Florida | ’97, ’98 Wilmington |
| 14 | 403 | Jason Dubois | VCU | Chicago (AL) | ’98 Rocky Mount |
| 15 | 431 | Tim Schilling | Elon | Florida | ’00 Peterburg |
| 15 | 441 | Daniel Hall | Campbell | Milwaukee | ’98 Rocky Mount/ ’99 Edenton |
| 15 | 443 | Chris Morris | The Citadel | St. Louis | ’98 Rocky Mount/ ’99 Florence |
| 15 | 453 | Brian Ross | Old Dominion | Cincinnati | ’99 Outer Banks |
| 15 | 459 | Julius Foreman | Augusta College | Arizona | ’00 Wilson |
| 17 | 495 | Derrick DePriest | North Carolina | Montreal | ’98 Durham |
| 17 | 501 | Daryl Clark | UNC- Charlotte | Milwaukee | ’00 Thomasville |
| 17 | 512 | Chris Elmore | North Carolina | Boston | ’99 Wilson |
| 21 | 630 | Kip Bouknight | South Carolina | Oakland | ’98 Wilson |
| 22 | 646 | Daniel Marsh | UNC- Wilmington | Tampa Bay | ’97 Outer Banks/ ’98 Wilmington |
| 22 | 663 | Clint Collins | South Carolina | Cincinnati | ’99 Florence |
| 23 | 678 | Tom Muldoon | Eckerd College | Detroit | ’98 Edenton |
| 23 | 685 | Chad Sadowski | Wisc.- Milwaukee | Philadelphia | ’98 Durham |
| 25 | 738 | Hugh Quattlebaum | Amherst College | Detroit | ’98 Durham |
| 27 | 800 | Zack Roper | Florida Atlantic | Anaheim | ’98 Edenton |
| 27 | 810 | Tripp Kelly | South Carolina | Oakland | ’99, ’00 Florence |
| 31 | 915 | Nick Schnabel | East Carolina | Montreal | ’99 Outerbanks |
| 32 | 965 | Tim LaVigne | Virginia | New York (NL) | ’99 Wilmington |
| 35 | 1031 | Micheal Oiler | Wisc.- Milwaukee | Milwaukee | ’99 Durham |
| 37 | 1098 | Matthew Walker | George Washington | Detroit | ’97 Wilmington |
| 42 | 1249 | Byron Batson | Campbell | Milwaukee | ’99 Wilmington |
| 43 | 1278 | Kevin Shrout | Virginia | Milwaukee | ’99 Wilmington |
| 48 | 1401 | Jason Hutton | UNC Charlotte | Chicago (AL) | ’99 Outerbanks |